Posters and Abstracts by Topic

SSIEM – Society for the Study of Inborn Errors of Metabolism – Hamburg, Germany, September 2007

• AT1001, A PHARMACOLOGICAL CHAPERONE DRUG CANDIDATE FOR THE TREATMENT OF FABRY DISEASE (poster)

ESHG European Human Genetics Conference, Nice France, June 2007

• THE PHARMACOLOGICAL CHAPERONE AT1001 INCREASES LEVELS OF Α-GALACTOSIDASE A IN FABRY PATIENT CELL LINES AND REDUCES GL-3 LEVELS IN A FABRY TRANSGENIC MOUSE MODEL (Poster)

American College of Medical Genetics, Nashville, Tennessee, March 2007

• THE PHARMACOLOGICAL CHAPERONE, AT1001, INCREASES LEVELS OF MUTANT AND WILD TYPE Α-GALACTOSIDASE A, THE ENZYME DEFICIENT IN FABRY DISEASE, IN VITRO, IN VIVO, AND IN A PHASE 1 CLINICAL TRIAL (Abstract)
• THE PHARMACOLOGICAL CHAPERONE AT1001 INCREASES LEVELS OF MUTANT AND WILD TYPE Α-GALACTOSIDASE A, THE ENZYME DEFICIENT IN FABRY DISEASE, IN VITRO, IN VIVO AND IN A PHASE 1 CLINICAL TRIAL
  (Poster)

SSIEM – Society for the Study of Inborn Errors of Metabolism – Hamburg, Germany, September 2007

• PHARMACOLOGICAL CHAPERONE THERAPY FOR THE TREATMENT OF GAUCHER DISEASE: AT2101 INCREASES ACID β-GLUCOSIDASE LEVELS IN CELLS, MICE AND HEALTHY HUMAN SUBJECTS (poster)

ESHG European Human Genetics Conference, Nice France, June 2007

• PHARMACOLOGICAL CHAPERONE-MEDIATED RESCUE OF MISFOLDED PROTEINS ASSOCIATED WITH GENETIC CONFORMATIONAL DISEASES (Abstract)

American College of Medical Genetics, Nashville, Tennessee, March 2007

• THE PHARMACOLOGICAL CHAPERONE ISOFAGOMINE INCREASES L444P GCASE LEVELS IN MICE WITH A GAUCHER DISEASE-LIKE PHENOTYPE (Abstract)
• A NEW APPROACH TO THE TREATMENT OF GAUCHER DISEASE: MECHANISM OF ENHANCEMENT OF N370S GCASE ACTIVITY (Abstract)
• PHASE 1 STUDIES OF THE SAFETY, PHARMACOKINETICS AND PHARMACODYNAMICS OF AT2101, A PHARMACOLOGICAL CHAPERONE FOR THE TREATMENT OF GAUCHER DISEASE (Abstract)
• PHASE 1 STUDIES OF THE SAFETY, PHARMACOKINETICS AND PHARMACODYNAMICS OF AT2101, A PHARMACOLOGICAL CHAPERONE FOR THE TREATMENT OF GAUCHER DISEASE (Poster)
• THE PHARMACOLOGICAL CHAPERONE ISOFAGOMINE INCREASES L444P GCASE LEVELS IN MICE WITH A GAUCHER DISEASE-LIKE PHENOTYPE (Poster